The mitral valve plays an important role in allowing blood to flow from the left upper chamber of the heart (left atrium) to the lower left chamber (left ventricle) while preventing backflow. Mitral valve disease can occur due to conditions like valve stenosis where the valve narrows and prevents normal blood flow or valve regurgitation where the valve leaks, allowing blood to flow backward. Traditionally mitral valve repair or replacement surgeries required open-heart surgery to access the valve through an incision in the chest. However, recently transcatheter mitral valve technologies have emerged as minimally-invasive alternatives to open-heart surgery for treating certain types of mitral valve disease.
Global mitral valve disease market is estimated to be valued at USD 2.80 Bn in 2024 and is expected to reach USD 5.12 Bn by 2031, exhibiting a compound annual growth rate (CAGR) of 9% from 2024 to 2031.
Key players
operating in the mitral valve replacement market are Edwards Lifesciences Corporation, Medtronic Plc, Abbott Laboratories, Boston Scientific Corporation, Corcym UK Limited, Artivion, Inc., ShockWave Medical, Inc., Valcare Medical, Braile Biomedica, Labcor Laboratorios Ltda, Zydus Lifesciences Limited, Affluent Medical, Teva Pharmaceutical Industries Ltd., Bayer AG, and Novartis AG
Market key trends:
One key trend gaining attention in the Mitral valve disease market size is the development of self-expanding transcatheter valves. Traditional transcatheter heart valves require ballooning or deployment systems to function, but newer self-expanding versions open and anchor themselves in place without the need for ballooning.
This results in simpler implantation procedures and reduces device interaction risks. Major manufacturers are investing in R&D to develop next-generation transcatheter valves centered around self-expansion capabilities for improving clinical outcomes.
Porter’s Analysis
Threat of new entrants: Mitral valve disease is a complex medical condition and high entry barriers prevent new companies from easily entering this market.
Bargaining power of buyers: Patients suffering from Mitral valve diseases have limited options and buying power due to the critical nature of the condition.
Bargaining power of suppliers: Key device and drug manufacturers dominate this market due to patented product portfolios and regulations limiting substitutes. Suppliers have significant influence over prices.
Threat of new substitutes: Few alternatives and substitutes exist for treating Mitral valve diseases. New treatments take significant time and capital to develop or receive approval.
Competitive rivalry:
Major players compete on innovation in devices and drugs. Companies are investing heavily in R&D for novel solutions to gain market share and competitive advantage in this large market. Mitral valve disease market Regional Analysis highlights how these efforts vary across regions, reflecting local needs, regulatory environments, and healthcare infrastructure.
The United States currently accounts for the largest share of the global Mitral valve repair and replacement device market in terms of value due to high adoption and reimbursement of advanced treatment options. The European region is another major market concentrated with key device manufacturers and an increasing patient population.
Asia Pacific region is witnessing the fastest market growth for Mitral valve diseases largely driven by expanding healthcare infrastructure, rising medical tourism and growing patient awareness in countries like India and China. Increased focus on developing inexpensive treatment alternatives is expected to boost the APAC Mitral valve market over the next decade.
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